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Next Subject		 Can mini/midiKros HF be used for outside-in filtration?DY2002-12-10Click here to register.
Hi

I am considering using the mini/midiKros hollow fiber filtration cartridges for a membrane suspended-growth bioreactor application. Specifically, it is for wastewater treatment, and I intend to recirculate the reactor supernatant (including biomass) through the membrane cartridge. The objectives are to increase the biomass concentration in the reactor and to provide a good quality effluent.

My concern with using the mini/midiKros systems is that they operate inside/out (i.e., the liquid flow goes through the inside of the fiber and the permeate goes to the outside of the fibers). Because the reactor will contain a high concentration of biomass, I am concerned about clogging the inside of the fibers due to biofilm growth, floc plugging, or scaling/precipitation. Most hollow-fiber membrane bioreactors for wastewater applications use an outside-in approach.

My questions are:
1) Are my concerns warranted? Perhaps the inner diameter is sufficient and the flow velocity will keep the lumen from clogging. Does anyone have experience with using mini/midiKros for wastewater applications?

2) I am considering running the mini/midiKros filtration cartridge outside-in, i.e., the filtrate will go into the lumen and be collected from the two ends. Under this configuration I will be pressurizing not the inside of the lumen but the outside. Would this cause a problem with either tubing connections, cartridge housing integrity, fiber integrity, etc? If not, how much pressure can safely be applied to not cause a leak in either housing or fiber?

If outside-in filtration is not recommended for mini/midiKros, does anyone know of any labscale hollow fiber cartidges that can be operated outside-in (preferably clear housing).
Thanks for your help.

Please email me reply to biotreat@yahoo.com
 
Re: Can mini/midiKros HF be used for outside-in filtration?
ppatel2002-12-11Click here to register.
Fiber's with 1.0 mm ID should allows for the recirculation of cellular suspensions. If the waste water sample has larger debris than single cells in suspension, then you should use the MidiKros or MiniKros Sampler "from the outside in". The potential problem that you may encounter is collapsing the fibers. Make sure that the extra-capillary pressure is no more than 5 PSI greater than the fiber lumen side. This maximum of 5 PSI difference will allow you to collect effluent from the lumen side without plugging the filter or collapsing the fiber

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